Systematic review and meta-analysis of animal models of tetrahydrocannabinol-induced psychosis

University of Edinburgh

Past award

Student: Angus Sinclair : University of Edinburgh

Year Award Started: 2015

Cannabis use is associated with an increased risk of psychosis in vulnerable people. Animal models
of psychosis are used to improve our understanding of the underlying causes of psychotic disorders
and to test potential therapies. Despite substantial animal research, there have been few advances
in treatments for those living with psychosis. To explore potential reasons for this failure to translate
positive finding in animals to humans, we will conduct a systematic assessment of all published
studies of animal models of psychosis induced by the primary psycho-active compound of cannabis,
tetrahydrocannabinol (THC).

Research area: Neurological conditions (including stroke)


Dr Gillian Currie
Centre for Clinical Brain Sciences