Estrogen, a potential cognitive enhancer: Evaluation of the regulation of glutamate receptor trafficking by estrogen

Clinical studies have shown that cognitive performance in women declines during the menopause and with ageing. This deficit has been linked to reductions in the levels of the hormone, oestrogen. Recent studies have shown that oestrogen greatly influences learning and memory processes. Consequently, oestrogen-based therapies may prevent or reverse age-related decline in memory in women. However our understanding of how oestrogen influences brain function is limited.