The role of the hippo pathway in colorectal cancer

University of St Andrews

Past award

Student: Abhinav Mathur : University of St Andrews

Year Award Started: 2013

Cancer is a leading health burden worldwide and more research is needed to understand the factors that drive cancers to grow. The Hippo pathway is a novel chemical signalling pathway inside cells that controls organ size and may lead to cancer formation when it becomes defective. We aim to investigate the role of this pathway in colorectal cancer to find out if it is a major growth driver. Recent data from colorectal cancers in mice provide a link, but are controversial. Our data may be useful to help doctors determine treatment options and may improve patient outcomes.

Research area: Cancer

Supervisors:

Dr Paul Reynolds
School of Medicine