Investigations into the association between endometriosis and natural killer cells

University of Edinburgh

Past award

Student: Sona Relovska : University of Edinburgh

Year Award Started: 2014

Endometriosis occurs when the lining of the womb (the endometrium) grows outside the womb, usually on the lining of the body cavity resulting in debilitating pelvic pain and infertility. The tissue fragments attract immune cells including natural killer (NK) cells. NK cells have the ability to kill other inappropriate cells present in the body. It is thought that NK cells might not function correctly in women with endometriosis, meaning that endometriosis cells are not killed and this may explain why they persist and grow. The aim of this project is to visualise NK cells in samples of endometriosis tissue from women and mice so we can learn more about their function and role in this disease.

Research area: Other conditions

Supervisors:

Professor Philippa Saunders
MRC Centre for Reproductive Biology