Investigating the neural basis for checking, selective attention, and working memory in obsessive compulsive disorder, through MEG and TMS

The most common subtype of Obsessive Compulsive Disorder (OCD) is characterized with repeated checking. Compulsive checking behaviours are associated with dysfunction and co-morbid anxiety disorders. Chronic checking symptomatology has been attributed to memory deficits. Neuroimaging techniques have been employed in an attempt to link behavioural and cognitive pathology to structural and physiological abnormalities in the brain. Under this neurocognitive framework, this study aims to identify the biological marker and predictors of the condition. The understanding of the neural underpinnings of OCD has the potential to develop a novel approach to treatment, and advise and reduce the cost of pharmacological experiments.