Incidence and pathophysiological significance of persistent myocardial oedema and haemorrhage in the infarct zone of heart attack survivors

University of Glasgow

Past award

Student: Jaclyn Carberry : University of Glasgow

Year Award Started: 2015

Heart attack causes sudden swelling, bruising and damage of the heart. Prompt restoration of blood
flow by re-opening the blocked coronary artery and use of cardioprotective medicines improves
survival after a heart attack. Since more patients are being treated effectively these days, more
people are surviving with injured hearts. Because of the initial heart damage, heart attack survivors
are at-risk of future heart failure, which is a debilitating condition. Our group has recently completed
one of the largest ever heart attack studies involving state-of-the-art cardiac magnetic resonance
imaging (MRI). 300 heart attack survivors had MRI 2 days and 6 months after emergency treatment
to open the blocked heart artery. To date we have focused on the early MRI scans. In this Vacation
Scholarship, we propose to 1) analyse the 6-month MRI scans for persistent oedema and
haemorrhage, and 2) assess the frequency and significance of these pathologies on heart function
and clinical outcomes.

Research area: Cardiovascular conditions


Professor Colin Berry
Institute of Cardiovascular and Medical Sciences