Efficacy of medical therapy in renovascular disease

Atherosclerotic renal artery stenosis (RAS) affects up to 5% of patients diagnosed with hypertension and is associated with increased risk for cardiovascular events and overall mortality. Current treatment options for RAS indicate medical therapy as first-line which commonly involves the use of ACE inhibitors (ACEIs) and angiotensin receptor blockers (ARBs), but they can have a side effect of impairing renal function. Retrospectively analysing data of patients prescribed these drugs will allow understanding of whether a type of anti-hypertensive drug correlates to improved patient outcomes. These results can potentially revise existing clinical guidelines on the medical therapy for patients with RAS.