Does Cidofovir increase human papillomavirus oncogenicity?

University of Glasgow

Past award

Student: Inari Kolu : University of Glasgow

Year Award Started: 2016

Cidofovir is a drug used to treat viral infections. In particular, it is used to treat recurrent respiratory papillomatosis (RRP) warts that are  caused by human papillomavirus (HPV) infection of the larynx.  Some years ago researchers propsed that Cidofovir many cause cancer formation in HPV-infected tissues. We have performed some experiments using short-term treatment with the drug that indicate that this is not true. We propose to  extend these obervations using longer term drug treatment with the aim to prove that Cidofovir remains a safe and effective drug for treating RRP.

Research area: Cancer


Professor Sheila Graham
Centre for Virus Research