Characterising the interaction of drug target mutants with host cells University of Glasgow Past award Student: Karen Crokston : University of Glasgow Year Award Started: 2012 We have previously found a group of drugs that interfere with how bacteria attach and infect human cells. However, working out how these drugs work is difficult. One step forward has been to find out what the targets of these drugs are. In this study we would like to see what happens to bacteria when we specifically remove one of these drug targets and will see if the bacteria can still infect human cells. This is an important step forward in understanding how these drugs work, which is essential if we want to make them even more potent. The longterm aim is to make a new class of anti-infective compounds to use clinically Supervisors: Dr Andrew Roe Institute of Infection, Immunity and Inflammation Back to all awards