Awards made during 1996-97
£9,935 to Dr Jane Norman and Professor Ian Greer (Obstetrics & Gynaecology, Glasgow Royal Infirmary, Dr Isobel Walker (Haematology, Glasgow Royal Infirmary) and Dr Alan Cameron (Obstetrics & Gynaecology, Queen Mother's Hospital, Glasgow) for a one-year study of the possible association of Factor V Leiden with recurrent miscarriage.
£61,457 to Drs Robin P. Alston, Michael Souter and Sheena Miller (Anaesthetics, Edinburgh Royal Infirmaty) and Dr Peter J.D. Andrews (Anaesthetics Western General Hospital, Edinburgh) for a one-year investigation into whether postoperative cerebral hypoperfusion only occurs following heart surgery.
£24,455 to Mr Ajith Siriwardena, Kenneth C.H. Fearon & James A. Ross (Surgery, Edinburgh Royal Infirmary) for a one-year, randomised controlled trial of early enteral nutrition in severe acute pancreatitis.
£68,806 to Professor Alison M. Gurney (Physiology & Pharmacology, Strathclyde University) for a two-year study aimed at developing a fluorescent assay for drugs that modulate pulmonary artery potassium channels.
£68,459 to Drs Alan R. Clarke, Sarah Howie, Colin Purdie & David J. Harrison (Pathology, Edinburgh University) for a two-year study which hopes to define the role of p53-dependent pathways in the normal and malignant development of murine T and B cells.
£85,285 to Mr Robert P. Mills (Otolaryngology, Ninewells Hospital & Medical School, Dundee) and Dr Eric W. Abel (Biomedical Engineering, Dundee University) for a two-year in vitro evalulation of physiological models of the ossicular chain.
£63,106 to Dr Scott Bader & Professor Andrew H. Wyllie (Pathology, Edinburgh University) for a two-year project aimed at the cloning and characterisation of a third family member of candidate tumour suppressor genes for human small cell lung cancer located on chromosome 3p21.
£34,396 to Drs Andrew J.R. Porter & Charles Cunningham (Molecular & Cell Biology, Aberdeen University) and Dr Grant Cumming (Obstetrics & Gynaecology, Aberdeen University) for a one-year project aimed at the isolation of a novel repertoire of auto-antigens associated with recurrent miscarriage.
£69,794 to Dr Tariq Sethi (Respiratory Medicine, Edinburgh University) and Dr Alison MacKinnon (Rayne Laboratory, Edinburgh University) for a two-year project to investigate the molecular mechanisms by which the 'broad spectrum neuropeptide antagonist' H-Arg-D-Trp-Nme-Phe-D-Trp-Leu-Met-NH2 inhibits small cell lung cancer cell growth and stimulates apoptosis.
£69,952 to Dr Jane Norman, Professor Ian Greer, Dr John A. Harper & Dr Charles B. Lunan (Obstetrics & Gynaecology, Glasgow Royal Infirmary) for a two-year study of the role of nitric oxide in human cervical ripening.
£39,824 to Dr Seamas Donnelly (Rayne Laboratory, Edinburgh University) & Professor Christopher Haslett (Respiratory Medicine, Edinburgh Royal Infirmary) for a one-year study of macrophage migration inhibotory factor (MIF) and inflammatory lung disease.
£74,224 to Dr Janet Liversidge (Ophthalmology) & Dr Graeme Nixon (Biomedical Sciences, Aberdeen University Medical School) for a two-year project for characterisation of the early endosomal compartment involved in the recycling of MHC Class II molecules and peptide exchange as an alternative pathway for presentation of autoantigens.
£69,954 to Professor Foo Y. Liew (Immunology, Glasgow University) for a two-year project involving the cloning of molecules on T cells inducible by IL-15 but not by IL-2 in rheumatoid arthritis using differential display and suprression subtractive hybridisation.
£50,818 to Drs Christopher Deighan & J.M. Boulton-Jones (Renal Unit) and Professor Christopher Packard and Dr M. Caslake (Pathological Biochemistry, Glasgow Royal Infirmary) for a one-year study of anbnormalities of lipoprotein metabolism in proteinuria and its role in cardiovascular risk and the progression of chronic renal failure.
£46,753 to Professor Allan Price (Clinical Oncology, Western General Hospital, Edinburgh) and Dr David J. Harrison (Pathology, Edinburgh University) for a two-year investigation of detoxification and DNA repair activities in patients with Grade IV toxicity folloiwng radiotherapy.
£2,960 to Drs Russell L. Woods & Stephen J. Tregear (Vision Sciences, Glasgow Caledonian University) to purchase a camera attachment for use in screening for diabetic retinopathy using cone-specific perimetry.
£25,963 to Dr Deborah Dewar (Wellcome Surgical Unit, Glasgow University) for a one-year in vitro study using organotypic slice cultures of presynaptic protein damage after ischaemia.
£78,82 to Dr Helen Lyall (Obstetrics & Gynaecology, Glasgow Royal Infirmary), Professor Iain T. Cameron (Obstetrics & Gynaecology, Queen Mother's Hospital Glasgow), Dr John R. Petrie & Professor John M. Connell (Medicine & Therapeutics, Western Infirmary Glasgow) and Dr Gwynn W. Gould (Biochemistry & Molecular Biology, Glasgow University) for a two-year study of insulin as a vascular hormone in women with polycystic ovary syndrome.
£94,237 to Dr Ian J. Holt (Molecular & Cellular Pathology, Ninewells Hospital & Medical School, Dundee) & Dr Alan R. Prescott (Biochemistry, Medical Science Institute, Dundee University) for a three-year project analysing innervated cultured muscle from patients with mitochondrial disease.
£30,391 to Dr Kieran Breen (Pharmacology, Ninewells Hospital & Medical School, Dundee) for a one-year study of the role of Tau protein glycosylation in the generation of neurofibrillary tangles associated with Alzheimer's Disease.
£99,697 to Dr Bruno Frenguelli (Pharmacology, Ninewells Hospital & Medical School, Dundee) for a three-year investigation into neuronal function after hypoxia/ischaemia in the in vitro rat hippocampal slice.
£37,464 to Dr Jamal Nasir (Molecular Genetics Centre, Western General Hospital, Edinburgh) for a one-year pilot study involving the development of animal models to test new approaches towards curing Huntingdon's disease.
£49,474 to Dr Peter T. Reid, Professor Christopher Haslett & Dr Jean-Michel Sallenave (Respiratory Medicine Unit, Rayne Laboratories, Edinburgh University) for a one-year study of inflammatory lung disease and the regulation of secretion of the low molecular weight antiproteinase elafin.
£40,177 to Drs Jonathan Berg, Mary Porteous & Susan Holloway (Clinical Genetics, Western General Hospital, Edinburgh) for an 18-month project to investigate whether gene expression and mutation in hereditary haemorrhagic telangiectasia may be the key to a new diagnostic test.
The Mrs Jean V. Baxter Medical Research Fellowship 1997-1999 was awarded to Dr Alasdair M.J. MacLullich (Rehabilitation Medicine, Astley Ainslie Hospital, Edinburgh) for a study of the association between glucocorticoids and brain ageing.